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However, clinical experience and trial data suggest the following approximate equivalencies: Semaglutide 0.5 mg weekly roughly corresponds to tirzepatide 2.5 mg to 5 mg weekly

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This distinction is important to avoid over treatment of older adults with mild hyperglycaemia while recommending intensive management in younger people to minimise diabetes complications

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doi: 10.1186/1758-5996-6-29 40 MoellmannJKlinkhammerBMOnsteinJSthrRJankowskiVJankowskiJet al